Born in Romania, Mariana Sirbu received her musical training from her parents. She completed her musical education in Bucharest at the National Academy of Music, under the guidance of Stefan Gheorghiu.
Her concert career started at a very early age, and brought her to virtually every country in Europe and overseas. Sirbu has been a prizewinner at international competitions such as George Enescu (Romania), Carl Flesch (London), Maria Canals (Barcelona), and Vittorio Gui (Florence).
After her graduation, Sirbu was an assistant teacher in Gheorghiu's violin class at the National Music Academy in Bucharest. She has taught numerous master classes in Spain, Ireland, Holland, Canada (The Banff Centre), France, China, Switzerland, Japan, and Italy. She taught violin and chamber music to post graduate students in the Scuola di Musica di Fiesole in Florence, Italy, and she is a guest professor at the University of Limerick-Ireland.
Sirbu has been a jury member in various international competitions, including the Banff International String Quartet Competition.